Abstract
The purpose of this study was to explore the relationship among the disability, health-promoting lifestyle and quality of life of SLE outpatients. A cross-sectional research design and purposive sampling were used in this study. One hundred and twenty nine SLE outpatients from a medical center were sampled. Adopted were the questionnaires including Visual Analogue Scale, the Pittsburgh Sleep Quality Index (PSQI) and the Hospital Anxiety and Depression scale in order to survey disability. The health-promoting lifestyle was measured by Health-Promoting lifestyle Profile, while the quality of life was collected by Short-Form 36.Hierarchical multiple regressions and sobel test were the major statistical procedures. The study results indicated that the SLE patient self-reported pain and fatigue related to the SLE disease were 27.7±26.2 and 37.4±26.6, respectively. Seventy two percent of the SLE patients were reported to be troubled by poor sleep quality, while 20-30% suffered from severe anxiety and depression problems. The health-promoting lifestyle total score of SLE patients was 61.5±17.2. In the dimensions of quality of life of SLE patients, the scores of physical component summary and mental component summary were 45.3±9.1 and 42.9±9.7, respectively. Based on the hierarchical multiple regressions and sobel test, it was revealed that fatigue was the incomplete mediator of health-promoting lifestyle to physical component summary of quality of life. Interestingly, the results showed facilitating health-promoting lifestyle in SLE patients could not enhance physical component summary of quality of life directly unless fatigue disability had been improved, whereas facilitating health-promoting lifestyle had a positive effect on mental component summary of quality of life directly.

Key words: Systematic Lupus Erythematosus, Disability, Health-promoting lifestyle, Quality of Life

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